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Dec 102015
Antibacterial Chemotherapy: Theory, Problems, and Practice (Oxford Infectious Diseases Library)Sebastian Amyes
Although antibiotics are among the most
widely used pharmaceuticals, they are also often inappropriately and
over-prescribed. Indeed there are increasing predictions that unless we
moderate our use of these drugs, bacterial resistance will eventually
render them useless. As there are no serious contenders to take the
place of antibiotics, including a failure to find new classes of these
drugs, it is essential for modern medicine that their efficacy is
preserved.
Part of the Oxford Infectious Disease Library, this pocketbook is
designed to help medical trainees, general prescribers, healthcare
workers and students of all biological and medical sciences to
understand how antibiotics work, to demonstrate where they might be most
appropriate and to make clear the threat of antibiotic resistance. In
particular, it will highlight the problems currently seen with bacteria
such as MRSA and describe the circumstances leading to their
persistence.
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Dec 102015
Attention-Deficit Hyperactivity Disorder and Hyperkinetic Disorder (Oxford Psychiatry Library)Tobias Banaschewski, David Coghill, Marina Danckaerts, Manfred Döpfner, Luis Rohde, Joseph A. Sergeant, Edmund J.S. Sonuga-Barke, Eric Taylor, Alessandro Zuddas
Attention deficit/hyperactivity disorder
(ADHD) is one of the most common mental disorders affecting children
and adolescents. The core ADHD symptoms are pervasive and impairing
inattention, hyperactivity, and/or impulsivity. Due to its significant
prevalence during the lifespan and associated impairments, the disorder
is considered a major health problem.
Despite a substantial increase in clinical and research interest in
ADHD in recent years, there is a relative lack of practical handbooks
and handy reference texts on the assessment and management of patients
with this condition.
Part of the Oxford Psychiatry Library, this pocketbook provides a user-friendly introduction to the diagnosis, evaluation, and treatment of ADHD.
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Dec 102015
Prostate Cancer (The Facts)Malcolm Mason, Leslie Moffat
Around 32,000 men in the UK are
diagnosed with prostate cancer each year. It differs from most other
cancers in the body, in that small areas of cancer within the prostate
are very common and may not grow or cause any problems for many years.
It is often it is diagnosed during a routine checkup so most men that
are diagnosed often have no warning signs.
About one in three men over the age of 50 have some cancer cells
within their prostate and nearly all men over the age of 80 have a small
area of prostate cancer. It may cause pain, difficulty in urinating,
erectile dysfunction and other symptoms, but early prostate cancer
usually causes no symptoms.
Since the first edition of this book was published in 2003, there have been several groundbreaking studies completed that have changed the way that certain categories of the disease are treated. This new edition of the book includes sections on radiotherapy, which is now known to be an effective treatment for men with residual prostate cancer after surgery, and a heavily updated chapter on Advanced Disease.
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Dec 102015
Atlas of Osteopathic TechniquesFeatures: Used Book in Good Condition Alexander Nicholas DO FAAO, Evan Nicholas DO
This highly praised atlas presents techniques commonly taught and
used in osteopathic medical education and practice, serving as an
authoritative reference for exam preparation and clinical rotations.
Step-by-step instructions, richly illustrated with full-color figures,
guide the learner through more than 350 manipulative methods.
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Dec 102015
Fibromyalgia For DummiesRoland Staud, Christine Adamec
The pain you suffer from fibromyalgia
syndrome (FMS) is not in your imagination. FMS is a real medical problem
that can be as debilitating and demoralizing as it is mysterious. Fibromyalgia For Dummies, Second Edition,
brings you the latest scientific findings on the symptoms and causes of
this disease and guides you toward proven, practical steps you can take
reduce or eliminate FMS-related pain.
This plain-English guide is fully updated with the latest
fibromyalgia treatment options, and evaluations of new medications that
have shown great promise in reducing pain. You’ll discover how to spot
an array of symptoms and their possible causes, work with your physician
to develop a treatment plan, and manage your pain at home and in the
office. You’ll learn how to:
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Dec 102015
Type 2 Diabetes: Methods and Protocols (Methods in Molecular Biology)
Diabetes is now reaching epidemic
proportions, and the associated complications of this disease can be
disabling and even life-threatening. In Type 2 Diabetes: Methods and Protocols,
leading investigators provide up-to-date explanations of commonly used
laboratory protocols used in diabetes research. Covering the commonly
described in vivo and in vitro model systems, the volume ultimately
leads to an overall view of how cellular dysfunction and degeneration
leads to susceptibility and diabetes disease progression. Written in the
highly successful Methods in Molecular Biology™ series format,
chapters include brief introductions to their respective subjects,
lists of the necessary materials and reagents, step-by-step, readily
reproducible protocols, and expert notes on troubleshooting and avoiding
known pitfalls.
Comprehensive and cutting-edge, Type 2 Diabetes: Methods and Protocols offers succinct, proven techniques to aid research scientists and clinicians in continuing the study of this debilitating disease.
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Dec 102015
Molecular Aspects of Innate and Adaptive Immunity: RSCFeatures: ISBN13: 9780854046980, Condition: New, Notes: 100% Satisfaction Guarantee. Tracking provided on most orders. Buy with Confidence! Millions of books sold!
The understanding, at the molecular
level, of the interactions between innate and adaptive arms of the
immune system is currently a hot topic, particularly to those interested
in immunology – especially susceptibility to infectious diseases. This
book provides a survey of topics, in the area of innate and adaptive
immunity, which have been researched within the MRC Immunochemistry
Unit, at Oxford University, over a period of forty years. The topics
include: ” antibody structure – for which the first Director of the
Immunochemistry Unit, Professor RR Porter, was awarded a Nobel prize in
1972 ” the characterization of membrane proteins on lymphoid cells –
leading to the concept of these molecules belonging to an immunoglobulin
super family ” the proteins of the human serum complement system – one
of the body’s major defences against microbial infection ” the human
cell -surface integrins and the hyaluronan- binding proteins, which are
involved in regulation of inflammation at cell surfaces and within the
extracellular matrix ” the family of collectin molecules – containing
distinct globular carbohydrate -binding domains linked to collagen-like
regions – which play important roles in innate immunity in the lungs and
bloodstream by immediate recognition and clearance of microbial
pathogens Each chapter in the book gives a brief historical background
to a topic and then provides a survey of recent advances in the field
and are written by internationally recognised renowned experts. The
theme running through the chapters is that of protein structure-function
relationships – including, amongst others, descriptions of quaternary
structures of large oligomeric proteins, of Factor H and C1q binding to
specific ligands, and of the chemistry of the mechanism of catalysis of
covalent binding of activated C3 and C4 proteins to nucleophilic groups
on microbial surfaces. In several chapters excellent descriptions are
given with respect to how the immune system can be recruited to combat
microbial infection – via proteins of both the innate and adaptive
immune systems. The book also includes notable chapters which are
excellent examples of the importance of how the isolation,
characterisation, protein engineering and crystallisation has resulted
in a full understanding of complex protein-protein interactions involved
in the recognition and triggering events of important sections of the
immune system: -Structure and Function of the C1 Complex – GÚrard J.
Arlaud -Chemical Engineering of Therapeutic Antibodies – George T
Stevenson -Leukocyte surface proteins – purification and
characterisation – A. Neil Barclay -Cell Surface Integrins – Suet-Mien
Tan and S.K. Alex Law This book is aimed primarily at established senior
research scientists, postdoctoral research scientists and PhD students
who have an interest in proteins of the immune system. However, the wide
range of immunity system topics, while staying broadly within
innate/adaptive immunity will also appeal to a wider audience.
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Dec 102015
Pharmaceutical Perspectives of Cancer Therapeutics
Pharmaceutical Perspectives of Cancer Therapeutics
covers a wide variety of therapeutic approaches including gene therapy,
immunological therapy; cancer vaccines; strategy for solid tumors as
well as for hematological cancers; methods to suppress tumor
angiogenesis and metastasis; development and utilization of relevant
animal models; introduction of new concepts such as cancer stem cells
and new technologies, such as DNA and tissue microarrays; and RNA
interference. In addition, clinical application, the development of DNA
diagnosis biomarkers and cancer prevention, as well as the utilization
of imaging in cancer therapy are also discussed. The use of synthetic
carriers, such as lipids, polymers, and peptides for delivery and
targeting of small molecules, proteins, and nucleic acids to cancer
cells in vivo are discussed. Pharmaceutical Perspectives of Cancer Therapeutics
also includes cancer therapy modality in surgery, chemotherapy, and
radiotherapy, as well as in combination or multi-modality, giving our
book a more focused view of cancer therapy.
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Dec 102015
Handbook of Drug Administration Via Enteral Feeding TubesJerry White, Rebecca White
The increase in awareness of the
importance of adequate nutritional intake has increased the use of
enteral feeding tubes for both short and long term feeding in both
primary and secondary care. An enteral feeding tube provides a means of
maintaining nutritional intake when there is limited access to the
gastrointestinal (GI) tract. Finding a suitable drug formulation for
administration to a patient with limited GI access can be difficult.
Although parenteral administration can be used and often guarantees 100
per cent absorption, repeated intravenous, subcutaneous or intramuscular
injections are associated with complications and are not suitable for
long-term use. There are also other routes that can be considered such
as transdermal, buccal, rectal or topical but the drugs available in
these preparations are limited. In these patients the feeding tube is
often the only means of enteral access and increasingly is being used as
a route for drug administration. However, their use for the
administration of drugs may induce formula intolerance, or result in
less than optimal drug absorption. This handbook is designed to provide
all the necessary guidance on the safe administration of medicines via
this route in one resource.
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Dec 102015
Preventing Miscarriage: The Good NewsJonathan Scher, Carol Dix
A Reassuring and Informative Guide
Along with inspiring accounts of women who have delivered healthy babies after years of heartbreak, Dr. Jonathan Scher
provides the latest medical information on preventing recurrent
miscarriages, including why couples with “unexplained infertility”
actually may be suffering repeat pregnancy loss due to failure of the
embryo to implant in the womb, important immunological and tissue tests
that may explain or prevent miscarriage, emerging treatments such as
heparin and I.V.I.G., updated resources, and much more.That Offers New Hope For Expectant Parents
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